傅容湛

姓名:傅容湛

院系:化工学院生物工程系 

职称: 副教授

出生日期: 1980.08

E-mail: rongzhanfu@bahriacommunity.com

联系电话: 029-88305118


主要研究领域:

天然产物功效学研究,抗癌药物,预防医学和营养医学,医用生物材料的设计与构建。


教育经历:

2007.2-2011.1,博士,生物化工专业,韩国科学技术院(KAIST);

2003.9-2006.7,硕士,生物化工专业,天博彩票;

1998.9-2002.7,学士,生物化工专业,天博彩票


工作经历:  

2017.07-今 天博彩票化工学院,生物医药研究院,副教授

2011-2013年 美国麻省理工学院(MIT)生物系研究助理及助教

2007-2011年 韩国科学技术院(KAIST)化工学院研究助理及助教


主持国家级科研项目:

1.国家自然科学基金委员会,青年科学基金项目,21808184,稀有人参皂苷Rk3诱导雌激素受体阳性乳腺癌细胞凋亡的抗肿瘤作用机制研究,2019-01-01 至 2021-12-31,28万元,主持

2.国家重点研发计划子课题,2021YFC2103500,一碳化合物生物转化制备燃料与化学品技术,2021-12 至 2024-11,100万元,主持

3.国家重点研发计划子课题,2021YFC2101500,天然活性产物生物制造技术,2021-07 至 2024-06,146万元,主持


专著或专著章节:

1. Emerging Technologies for Biorefineries, Biofuels, and Value-Added Commodities, Springer Nature, 2021, 参编Chapter 10: Advanced fermentation strategies to enhance lipid production.

2. Direct Natural Gas Conversion to Value-Added ChemicalsCRC press, 2020, 参编Chapter 14Biological Conversion of Natural Gas


代表性论文 :

1. WanyiZhou, ZhiguangDuan, JingZha, RongzhanFu*, ChenhuiZhu*, DaidiFan*, Glucose and MMP-9 dual-responsive hydrogel with temperature sensitive self-adaptive shape and controlled drug release accelerates diabetic wound healing, Bioactive Materials, 2022, 17,1-17

2. Yang Li*, Rongzhan Fu*, Zhiguang Duan, Chenhui Zhu,* and Daidi Fan*,Injectable Hydrogel Based on Defect-Rich Multi-Nanozymes for Diabetic Wound Healing via an OxygenSelf-Supplying Cascade Reaction. 2022, Small, DOI: 10.1002/smll.202200165

3. Haoping Lu; Huayu Yin; Linlin Qu; Xiaoxuan Ma; Rongzhan Fu*and Daidi Fan*, Ginsenoside Rk1 regulates glutamine metabolismin hepatocellular carcinoma through inhibition ofthe ERK/c-Myc pathway.Food & Function, 2022, DOI: 10.1039/d1fo03728e

4. Xue Bai; Rongzhan Fu; Zhiguang Duan; Pan Wang; Chenhui Zhu; Daidi Fan; Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice, Food Research International, 2021, 146: 110465-110476

5. Xue Bai; Rongzhan Fu; Zhiguang Duan; Yannan Liu; Chenhui Zhu; Daidi Fan ; Ginsenoside Rh4alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition, Food & Function, 2021, 9: 20483-20491

6. Linlin Qu#; Rongzhan Fu#; Xiaoxuan Ma; Daidi Fan; Hepatoprotective effects of ginsenosideRk3 in acetaminophen-induced liver injury in mice by activation of autophagy, Food & Function, 2021, 12: 9128-9140

7. Linlin Qu; Rongzhan Fu; Xiaoxuan Ma; Daidi Fan ; Protopanaxatriol-type saponin protects against acetaminophen-induced liver injury through ROS-mediated JNK pathway, Journal of FunctionalFoods, 2021, 86: 104672

8. Rongzhan Fu; Qiang Fei; Longan Shang; Christopher J. Brigham; Ho Nam Chang ; Enhanced microbial lipid production by Cryptococcus albidus in the high-cell-density continuous cultivation with membrane cell recycling and two-stage nutrient limitation, Journal of Industrial Microbiology& Biotechnology, 2018, 45: 1045-1051

9. Ning Mou, Zhiguang Duan, Pei Ma, Rongzhan Fu* and Daidi Fan *,Study on the hypnotic effect of rare protopanaxadiol-type and protopanaxatriol-type ginsenosides,RSC Adv., 2019, 9, 20483-20491

10. Ya Wang#, Rongzhan Fu#, Zhiguang Duan#, Xijuan Jiang, Chenhui Zhu and Daidi Fan *,Inorganic salt transition states: a stable and highly stretchable elastomer-like phase (ELP) of phosphate salts at the air–solid interface,Chem. Commun., 2018, 54, 9973-9976

11. Rongzhan Fu,Qiang Fei*, Longan Shang, Christopher J. Brigham, Ho Nam Chang, Enhanced microbial lipid production by Cryptococcus albidus in the high-cell-density continuous cultivation with membrane cell recycling and two-stage nutrient limitation, Journal of Industrial Microbiology & Biotechnology, 2018, 45, 1045–1051

12. Rongzhan Fu, Taihua Li, Soo Suk Lee, Hyun Gyu Park*, 2011, DNAzyme Molecular Beacon Probes for Target-Induced Signal Amplifying Colorimetric Detection of Nucleic Acids. Analytical Chemistry, 83(2), 494.

13. Rongzhan Fu, Taihua Li, Hyun Gyu Park*, 2009. An ultrasensitive DNAzyme-based colorimetric strategy for nucleic acid detection. Chemical Communications. 5838.

14. Rongzhan Fu, Taihua Li, Hyun Gyu Park*, Peroxidase 2011, An ultrasensitive peroxidase DNAzyme-associated aptasensor that utilize a target-triggered enzymatic signal amplification strategy, Chemical Communications, 47(35), 9876.

15. Taihua Li, Rongzhan Fu, Hyun Gyu Park*, 2010. Pyrrolo-dC based fluorescent aptasensors for the molecular recognition of targets. Chemical Communications. 3271.

16. Byoung Yeon Won, Sujeong Shin, Rongzhan Fu, Dae-Yeon Cho and Hyun Gyu Park*, 2011, A one-step electrochemical method for DNA detection that utilizes a peroxidase-mimicking DNAzyme amplified through PCR of target DNA. Biosensors and Bioelectronics, 30(1), 73.

17. Qiang Fei, Rongzhan Fu, Longan Shang, Christopher J Brigham, Ho Nam Chang*. 2014, Lipid production by microalgae Chlorella protothecoides with volatile fatty acids (VFAs) as carbon sources in heterotrophic cultivation and its economic assessment. Bioprocess Biosyst Eng, 38, 691.